Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.47 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.47 |
| ▸ | ATR | Q13535 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16691871 | 0.91 | KDM1A (0.51) | ALDH1A1LMNAKDM4ERAB9AMAPT | |
| SCHEMBL20527216 | 0.88 | P2RY12 (0.46) | POLBALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL21451882 | 0.85 | PTPN1 (0.46) | POLBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL16710973 | 0.85 | MAPT (0.48) | POLBALDH1A1LMNAKDM4ERAB9A | |
| Hydrochloric Acid SCHEMBL20527158 | 0.84 | PTPN1 (0.44) | POLBALDH1A1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL16693559 | 0.84 | RAB9A (0.54) | POLBALDH1A1LMNAKDM4ERAB9A | |
| SCHEMBL16710925 | 0.82 | P2RY12 (0.48) | POLBRAB9AMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27118770 | 0.81 | CYP17A1 (0.46) | POLBMEN1KMT2ATHRBP2RY14 | |
| SCHEMBL16691884 | 0.79 | NAMPT (0.60) | ALDH1A1LMNAKDM4ERAB9AMAPT | |
| SCHEMBL16710979 | 0.79 | MAPT (0.45) | POLBALDH1A1LMNAKDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127332-A1 | CYTOTOXIC COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2024-06-20 | — | — | WO | disclosed |