Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 2/20 | 0.69 |
| ▸ | CDK8 | P49336 | 2/20 | 0.69 |
| ▸ | BRD4 | O60885 | 2/20 | 0.53 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.53 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | ICMT | O60725 | 3/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12582221 | 0.84 | CCNC (0.49) | CCNCCDK8BRD4BRD9KIF11 | |
| SCHEMBL16115074 | 0.81 | CCNC (1.00) | CCNCCDK8BRD4BRD9PIM1 | |
| SCHEMBL12582220 | 0.80 | NR4A2 (0.46) | CCNCCDK8PKM | |
| SCHEMBL14379383 | 0.78 | BAZ2B (0.48) | CCNCCDK8 | |
| SCHEMBL10002537 | 0.77 | CDK8 (0.51) | CCNCCDK8BRD4BRD9PIM1 | |
| SCHEMBL27296169 | 0.74 | POLB (0.49) | — | |
| SCHEMBL28811450 | 0.72 | CCNC (0.50) | CCNCCDK8BRD4PKMPARP1 | |
| SCHEMBL16710973 | 0.71 | MAPT (0.48) | KIF11 | |
| SCHEMBL13527129 | 0.70 | CCNC (0.51) | CCNCCDK8BRD4BRD9PIM1 | |
| SCHEMBL19151400 | 0.70 | CCNC (0.51) | CCNCCDK8BRD4BRD9PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024127332-A1 | CYTOTOXIC COMPOUNDS | PHEON THERAPEUTICS LTD (GB) | 2024-06-20 | — | — | WO | disclosed |