Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27296836 | 0.81 | MAPT (0.35) | MAPTKDM4E | |
| SCHEMBL3668490 | 0.79 | CYP2A6 (0.35) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25376794 | 0.76 | — | — | |
| SCHEMBL12134841 | 0.72 | CYP1A2 (0.44) | MAPTKDM4EHSP90AA1LMNAALDH1A1 | |
| SCHEMBL31685067 | 0.72 | CYP1A2 (0.44) | MAPTKDM4EHSP90AA1LMNAALDH1A1 | |
| SCHEMBL27296163 | 0.72 | ALDH1A1 (0.37) | MAPTKDM4ELMNAHTTMEN1 | |
| SCHEMBL29417321 | 0.71 | NR4A2 (0.46) | MAPTLMNANPC1RAB9A | |
| SCHEMBL2916780 | 0.71 | NR4A2 (0.46) | MAPTLMNANPC1RAB9A | |
| SCHEMBL30515553 | 0.68 | MAPT (0.34) | MAPTKDM4EHSP90AA1LMNAHTT | |
| SCHEMBL8139070 | 0.68 | DHODH (0.39) | MAPTKDM4ELMNAALDH1A1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4617262-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Kyoto University (JP) | 2025-09-17 | — | — | EP | disclosed |
| WO-2024101336-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | 国立大学法人京都大学 | 2024-05-16 | — | — | WO | disclosed |
| WO-2024101336-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | 国立大学法人京都大学 | 2024-05-16 | — | — | WO | disclosed |