Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844195 | 0.85 | LOXL2 (0.69) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL17921221 | 0.81 | LOXL2 (0.65) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL1254026 | 0.81 | LOXL2 (0.76) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL13143573 | 0.79 | LOXL2 (0.61) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL13179819 | 0.79 | LOXL2 (0.61) | LOXL2MCL1OGG1GPR3CD274 | |
| SCHEMBL660485 | 0.79 | LOXL2 (0.61) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL7896583 | 0.79 | LOXL2 (1.00) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL6481714 | 0.79 | LOXL2 (0.71) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL660322 | 0.77 | LOXL2 (0.59) | LOXL2MCL1OGG1GPR3HDAC1 | |
| SCHEMBL11210513 | 0.77 | LOXL2 (0.59) | LOXL2MCL1OGG1CD274ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035116-A | Heterocyclic type oxo-2 guanidine-acetic acid | PFIZER (US) | 1989-08-30 | — | — | CN | disclosed |