SCHEMBL27296641

SCHEMBL27296641

Cn1cnnc1-c1ccc(C#N)cc1-c1cc(NCC2(CC#N)CC2)nc(N2Cc3c(cc(CN4CCOCC4)cc3C(F)(F)F)C2=O)c1

nearest known ligand 0.55

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27299153 0.92 CBLB (0.60) CBLB
SCHEMBL27293249 0.92 CBLB (0.55) CBLB
SCHEMBL27294883 0.91 CBLB (0.55) CBLB
SCHEMBL27300356 0.90 CBLB (0.53) CBLB
SCHEMBL27300354 0.90 CBLB (0.53) CBLB
SCHEMBL27296642 0.88 CBLB (0.56) CBLB
SCHEMBL27299554 0.86 CBLB (0.55) CBLB
SCHEMBL27298611 0.85 CBLB (0.54) CBLB
SCHEMBL27295590 0.85 CBLB (0.57) CBLB
SCHEMBL27295027 0.85 CBLB (0.57) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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