SCHEMBL27299153

SCHEMBL27299153

Cn1cnnc1-c1ccc(C#N)cc1-c1cc(NCC2(CC#N)CC2)nc(N2Cc3c(cc(CO)cc3C(F)(F)F)C2=O)c1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.60
▸ CBLC Q9ULV8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27296641 0.92 CBLB (0.55) CBLB
SCHEMBL27293249 0.91 CBLB (0.55) CBLB
SCHEMBL27287964 0.90 CBLB (0.59) CBLB
SCHEMBL30956927 0.90 CBLB (0.57) CBLB
SCHEMBL27308801 0.90 CBLB (0.57) CBLB
SCHEMBL30956967 0.89 CBLB (0.57) CBLB
SCHEMBL27290466 0.89 CBLB (0.57) CBLB
SCHEMBL29920684 0.89 CBLB (0.62) CBLB
SCHEMBL27085877 0.89 CBLB (0.62) CBLB
SCHEMBL27300354 0.88 CBLB (0.53) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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