Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 6/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.41 |
| ▸ | WNT1 | P04628 | 5/20 | 0.41 |
| ▸ | EP300 | Q09472 | 10/20 | 0.41 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2726267 | 1.00 | GPR55 (0.42) | GPR55CREBBPGSK3BDYRK1AWNT1 | |
| SCHEMBL2726258 | 1.00 | GPR55 (0.42) | GPR55CREBBPGSK3BDYRK1AWNT1 | |
| SCHEMBL2730077 | 0.91 | GPR55 (0.41) | GPR55CREBBPGSK3BDYRK1AWNT1 | |
| SCHEMBL2730245 | 0.88 | EP300 (0.40) | GPR55CREBBPEP300 | |
| SCHEMBL2730243 | 0.88 | EP300 (0.40) | GPR55CREBBPEP300 | |
| Hydrochloric Acid SCHEMBL2727529 | 0.82 | STING1 (0.40) | CREBBPGSK3BDYRK1AWNT1EP300 | |
| Hydrochloric Acid SCHEMBL2727535 | 0.82 | STING1 (0.40) | CREBBPGSK3BDYRK1AWNT1EP300 | |
| SCHEMBL2729210 | 0.81 | EP300 (0.36) | GPR55GSK3BDYRK1AWNT1EP300 | |
| SCHEMBL2729213 | 0.81 | EP300 (0.36) | GPR55GSK3BDYRK1AWNT1EP300 | |
| SCHEMBL2716020 | 0.81 | CDK7 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445909-B1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INT (DE) | 2013-11-13 | — | — | EP | disclosed |
| EP-2445909-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | Boehringer Ingelheim International GmbH (DE) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010141273-A1 | DERIVATIVES OF 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOLE-3-CARBOXYLIC ACID AMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-12-09 | — | — | WO | disclosed |