Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
| ▸ | CCR8 | P51685 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Chloropyridine SCHEMBL28283236 | 0.84 | TDP1 (0.64) | TDP1NPC1RAB9AMEN1KMT2A | |
| Tert-Butyl Formate SCHEMBL27549647 | 0.83 | TDP1 (0.57) | TDP1NPC1RAB9AMEN1KMT2A | |
| 2-Chloropyridine SCHEMBL27506304 | 0.83 | TDP1 (0.76) | TDP1NPC1RAB9AMEN1KMT2A | |
| 2-Chloropyridine SCHEMBL27596465 | 0.81 | TDP1 (0.73) | TDP1NPC1RAB9AMEN1KMT2A | |
| 2-Chloropyridine SCHEMBL27294981 | 0.81 | TDP1 (0.73) | TDP1NPC1RAB9AMEN1KMT2A | |
| 2-Chloropyridine SCHEMBL28292211 | 0.81 | TDP1 (0.73) | TDP1NPC1RAB9AMEN1KMT2A | |
| 2-Chloropyridine SCHEMBL9366854 | 0.80 | — | — | |
| 2-Chloropyridine SCHEMBL27450572 | 0.80 | — | — | |
| 2-Chloropyridine SCHEMBL10690176 | 0.80 | TDP1 (1.00) | TDP1NPC1RAB9AMEN1KMT2A | |
| 2-Chloropyridine SCHEMBL16637 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563057-A | Sulfonamide compounds or its salt | 大鹏药品工业株式会社 | 2019-04-02 | — | — | CN | disclosed |
| CN-109503637-A | For treating the noval chemical compound of the disease of helminth | 安纳考尔医药公司 | 2019-03-22 | — | — | CN | disclosed |
| CN-104114543-B | Therapeutically active compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2019-03-15 | — | — | CN | disclosed |
| CN-109153688-A | Oxaborolidine esters and uses thereof | 安纳考尔医药公司 | 2019-01-04 | — | — | CN | disclosed |
| CN-108912066-A | Therapeutical active compound and its application method | 安吉奥斯医药品有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-108884078-A | Glycosidase inhibitor | 阿森纽荣股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-108884077-A | Glycosidase inhibitors | 阿森纽荣股份公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-105492435-B | Compound as IDH2 mutant inhibitor | 安吉奥斯医药品有限公司 | 2018-06-29 | — | — | CN | disclosed |
| CN-108137545-A | TRIAZOLE AGONISTS OF THE APJ RECEPTOR | 美国安进公司 | 2018-06-08 | — | — | CN | disclosed |
| CN-105121427-B | Pyridine radicals and condensed pyridine base triazolone derivative | 武田药品工业株式会社 | 2018-04-10 | — | — | CN | disclosed |
| CN-107417667-A | Therapeutical active compound and its application method | 安吉奥斯医药品有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107426998-A | The recovery of palladium catalyst and/or recycling after Suzuki coupling | 美国陶氏益农公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-1039080-C | Herbicidal carboxamide derivatives | SHELL INT RESEARCH (NL) | 1998-07-15 | — | — | CN | disclosed |
| CN-1036239-C | Herbicidal carboxamide derivatives | SHELL INT RESEARCH (NL) | 1997-10-29 | — | — | CN | disclosed |