(Z)-1,2-Diphenylethene

(Z)-1,2-Diphenylethene

SCHEMBL272984

C(=C/c1ccccc1)\c1ccccc1.O=C1C=CC(=O)C=C1

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 3/20 0.52
ALDH1A1 P00352 3/20 0.50
LMNA P02545 3/20 0.50
NFE2L2 Q16236 2/20 0.50
CYP19A1 P11511 2/20 0.50
MAOA P21397 2/20 0.50
CMA1 P23946 1/20 0.50
TRPA1 O75762 1/20 0.50
ALOX5 P09917 1/20 0.50
MAPK1 P28482 1/20 0.50
CYP1A2 P05177 2/20 0.48
HDAC1 Q13547 2/20 0.48
HDAC3 O15379 1/20 0.48
TNKS O95271 1/20 0.48
HDAC4 P56524 1/20 0.48
HCAR2 Q8TDS4 1/20 0.48
HDAC7 Q8WUI4 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC10 Q969S8 1/20 0.48
HDAC11 Q96DB2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(Z)-1,2-Diphenylethene SCHEMBL442 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL347707 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9488270 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9134305 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9134296 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL9488275 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL443 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL22712863 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
(Z)-1,2-Diphenylethene SCHEMBL21847984 0.82 MAOB (0.73) MAOBALDH1A1LMNANFE2L2CYP19A1
SCHEMBL11749666 0.80 CMA1 (0.58) MAOBALDH1A1LMNACMA1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110832403-B Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2023-09-22 CN claimed
CN-111108443-A Electrophotographic photoreceptor, method for producing electrophotographic photoreceptor, and electrophotographic apparatus 富士电机株式会社 2020-05-05 CN claimed
CN-110832403-A Electrophotographic photoreceptor, method for producing the same, and electrophotographic apparatus 富士电机株式会社 2020-02-21 CN claimed
US-8133482-B2 Conjugate comprising substrate linked to cell death protease recognition sequence, photoactivatable killing agent and quencher; decontaminating blood, treating cancer or viral infections THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2012-03-13 US claimed
US-20080193431-A1 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS UNIVERSITY OF PENNSYLVANIA (US) 2008-08-14 US claimed
WO-2005048944-A2 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS UNIVERSITY OF PENNSYLVANIA (US) 2005-06-02 WO claimed
CN-117343770-B Dielectric fluid comprising natural bio-derived oil with increased stability 嘉吉公司 2026-05-19 CN disclosed
CN-116884670-B Synthetic esters and mineral oil dielectric fluids with increased stability 嘉吉公司 2025-02-18 CN disclosed
CN-119486870-A Recyclable multilayer structure for fluid transport, distribution or storage applications 阿科玛法国公司 2025-02-18 CN disclosed
EP-4446310-A1 METHOD FOR PRODUCING BLOCKED ISOCYANATE COMPOUND AND METHOD FOR PRODUCING ISOCYANATE COMPOUND Asahi Kasei Kabushiki Kaisha (JP) 2024-10-16 EP disclosed
CN-118382612-A Method for producing blocked isocyanate compound and method for producing isocyanate compound 旭化成株式会社 2024-07-23 CN disclosed
CN-113196881-B Electroluminescent element and display device 夏普株式会社 2024-05-14 CN disclosed
CN-117343770-A Dielectric fluid comprising natural bio-derived oil with increased stability 嘉吉公司 2024-01-05 CN disclosed
US-4100204-A Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of a hydroxy- or keto-acid compound ICI AMERICAS INC. (US) 1978-07-11 US disclosed
US-4098830-A OXIDATIVE COUPLING OF ALKYLPHENOLS OR 1-NAPHTHOLS CATALYZED BY METAL COMPLEXES OF DICARBOXYLIC ACID COMPOUNDS ICI AMERICAS INC. (US) 1978-07-04 US disclosed
US-4097461-A Oxidative coupling of alkylphenols or 1-naphthols catalyzed by metal complexes of diketo compounds ICI AMERICAS INC. (US) 1978-06-27 US disclosed
US-4096190-A Oxidative coupling of alkylphenols catalyzed by metal ammonia complexes ICI AMERICAS INC. (US) 1978-06-20 US disclosed
US-4085124-A Oxidative coupling of alkylphenols, alkoxyphenols and 1-naphthols catalyzed by metal complexes of amino compounds ICI AMERICAS INC. (US) 1978-04-18 US disclosed
US-4070383-A COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM ICI AMERICAS INC. (US) 1978-01-24 US disclosed
US-4067890-A Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids ICI AMERICA INC. (US) 1978-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080193431-A1 ACTIVATABLE PHOTODYNAMIC THERAPY AGENTS HMBS, CD47, APEX1 MAOB 1147/4885ALDH1A1 101/4885LMNA 3648/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.