Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3382791 | 0.85 | KDM1A (0.40) | AKT2 | |
| SCHEMBL22387918 | 0.75 | PDE10A (0.37) | PDE10A | |
| SCHEMBL29908263 | 0.73 | DPP4 (0.38) | ADRA2AADRA2CAKT2LMNAHIF1A | |
| SCHEMBL22927815 | 0.73 | DPP4 (0.38) | ADRA2AADRA2CAKT2LMNAHIF1A | |
| SCHEMBL2791956 | 0.71 | PDE10A (0.39) | PDE10AADRA2AADRA2CKDM4E | |
| SCHEMBL31473371 | 0.71 | PDE10A (0.39) | AOC3PDE10A | |
| SCHEMBL27299154 | 0.71 | PDE10A (0.39) | AOC3PDE10A | |
| SCHEMBL3386704 | 0.69 | AKT2 (0.41) | ADRA2AADRA2CAKT2LMNAHIF1A | |
| SCHEMBL14808807 | 0.69 | DPP4 (0.38) | AKT2HTR2A | |
| SCHEMBL3382818 | 0.69 | CYP3A4 (0.42) | AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119866333-A | KIT inhibitors, compounds, pharmaceutical compositions, and methods of use thereof | 亚力维克希斯股份有限公司 | 2025-04-22 | — | — | CN | disclosed |
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |