SCHEMBL27299296

SCHEMBL27299296

CC(C)CNc1cc(-c2cc(C#N)ccc2-c2nncn2C)cc(N2Cc3c(cc(CN4C[C@H]5CCC[C@H]5C4)cc3C(F)(F)F)C2=O)n1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ CBLB Q13191 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27299054 0.93 CBLB (0.57) CBLB
SCHEMBL27298950 0.92 CBLB (0.56) CBLB
SCHEMBL27292964 0.92 CBLB (0.55) CBLB
SCHEMBL27299449 0.91 CBLB (0.55) CBLB
SCHEMBL27299450 0.91 CBLB (0.55) CBLB
SCHEMBL27299061 0.91 CBLB (0.54) CBLB
SCHEMBL27299451 0.90 CBLB (0.58) CBLB
SCHEMBL27294735 0.90 CBLB (0.58) CBLB
SCHEMBL27298613 0.90 CBLB (0.56) CBLB
SCHEMBL27298335 0.90 CBLB (0.56) CBLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024081311-A1 CBL-B MODULATORS AND USES THEREOF NIMBUS CLIO, INC. (US) 2024-04-18 — — WO disclosed
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