SCHEMBL27299461

SCHEMBL27299461

CCCCCCC(CSCCCCCC(CCCCCSCC(CCCCCC)OC(=O)CCC1CCCCC1)N(C)CCCCO)OC(=O)CCC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 4/20 0.35
▸ PRKD3 O94806 1/20 0.32
▸ PRKCG P05129 1/20 0.32
▸ PRKCB P05771 1/20 0.32
▸ PRKCA P17252 1/20 0.32
▸ PRKCH P24723 1/20 0.32
▸ PRKCI P41743 1/20 0.32
▸ PRKCE Q02156 1/20 0.32
▸ PRKCQ Q04759 1/20 0.32
▸ PRKCZ Q05513 1/20 0.32
▸ PRKCD Q05655 1/20 0.32
▸ PRKD1 Q15139 1/20 0.32
▸ MAPT P10636 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ NAAA Q02083 1/20 0.31
▸ CNR1 P21554 1/20 0.30
▸ DAGLA Q9Y4D2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30977743 0.94 TLR2 (0.33) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL27299109 0.93 TLR2 (0.33) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL27299259 0.92 TLR2 (0.32) TLR2
SCHEMBL27299469 0.92 TLR2 (0.33) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL27299467 0.91 TLR2 (0.32) TLR2MAPTMAPK1NAAA
SCHEMBL27299464 0.90 TLR2 (0.34) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL27303924 0.89 TLR2 (0.37) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL30837983 0.87 MAPT (0.44) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL30837980 0.87 MAPT (0.44) TLR2PRKD3PRKCGPRKCBPRKCA
SCHEMBL30837956 0.87 MAPT (0.44) TLR2PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4638417-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS Nanovation Therapeutics Inc. (CA) 2025-10-29 — — EP disclosed
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-12-05 — — US disclosed
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents NANOVATION THERAPEUTICS INC. (CA) 2024-10-22 — — US disclosed
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-08-08 — — US disclosed
WO-2024130421-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-06-27 — — WO disclosed
WO-2024130421-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS NANOVATION THERAPEUTICS INC. (CA) 2024-06-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12121591-B2 Sulfur-containing ionizable lipids for the delivery of nucleic acids and other therapeutic agents SLC43A1, NSUN3, NSUN2 TLR2 3615/4885PRKD3 3386/4885PRKCG 2536/4885
US-20240261430-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 TLR2 3615/4885PRKD3 3386/4885PRKCG 2536/4885
US-20240398977-A1 SULFUR-CONTAINING IONIZABLE LIPIDS FOR THE DELIVERY OF NUCLEIC ACIDS AND OTHER THERAPEUTIC AGENTS SLC43A1, NSUN3, NSUN2 TLR2 3615/4885PRKD3 3386/4885PRKCG 2536/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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