Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.46 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27096948 | 0.86 | HTR2A (0.52) | HTR2AHTR2CSLC6A4HTR2BPOLB | |
| SCHEMBL30729931 | 0.86 | HTR2A (0.52) | HTR2AHTR2CSLC6A4HTR2BPOLB | |
| SCHEMBL27096888 | 0.81 | MAPT (0.48) | HTR2AHTR2CSLC6A4HTR2BPOLB | |
| SCHEMBL27299484 | 0.77 | RAB9A (0.46) | POLBMRGPRX4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10227870 | 0.75 | MRGPRX4 (0.53) | MRGPRX4RAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL12524878 | 0.75 | MRGPRX4 (0.50) | POLBMRGPRX4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7861771 | 0.75 | SMN1; SMN2 (0.71) | POLBRAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL14777185 | 0.74 | FFAR1 (0.50) | HTR2AHTR2CSLC6A4HTR2BPOLB | |
| SCHEMBL2760112 | 0.74 | SYK (0.59) | SLC6A4MRGPRX4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11911910 | 0.73 | HTR2A (0.50) | HTR2AHTR2CSLC6A4HTR2BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |