Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12409075 | 0.86 | NPC1 (0.50) | KMT2AMEN1MAPK1NPC1RAB9A | |
| SCHEMBL4030728 | 0.84 | KMT2A (0.44) | KMT2AMEN1MAPK1TP53HTT | |
| SCHEMBL27299192 | 0.82 | KMT2A (0.45) | KMT2AMEN1MAPK1TP53HTT | |
| SCHEMBL14174985 | 0.75 | KMT2A (0.68) | KMT2AMEN1TP53NPC1RAB9A | |
| SCHEMBL8308040 | 0.74 | MEN1 (0.45) | KMT2AMEN1HTTNPC1RAB9A | |
| SCHEMBL15704234 | 0.73 | MEN1 (0.53) | KMT2AMEN1TP53HTTNPC1 | |
| SCHEMBL4856194 | 0.73 | TSHR (0.51) | KMT2AMEN1MAPK1HTTNPC1 | |
| SCHEMBL169716 | 0.73 | MRGPRX4 (0.53) | KMT2AMEN1MAPK1TP53HTT | |
| SCHEMBL13929749 | 0.72 | MRGPRX4 (0.58) | KMT2AMEN1MAPK1NPC1RAB9A | |
| SCHEMBL8308033 | 0.71 | MEN1 (0.45) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026056-A2 | HETEROARYL COMPOUNDS AS EGFR INHIBITORS AND THEIR USES | ACCUTAR BIOTECHNOLOGY, INC. (US) | 2024-02-01 | — | — | WO | disclosed |