Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13774960 | 0.88 | NCF1 (0.46) | NCF1 | |
| SCHEMBL13775366 | 0.88 | NCF1 (0.46) | NCF1 | |
| SCHEMBL12435319 | 0.88 | NCF1 (0.46) | NCF1 | |
| SCHEMBL26750312 | 0.81 | ATM (0.35) | NCF1LMNACA1CA2CA4 | |
| SCHEMBL20250800 | 0.81 | ATM (0.35) | NCF1LMNACA1CA2CA4 | |
| SCHEMBL18085509 | 0.80 | CA1 (0.54) | NCF1ALDH1A1HTTLMNACA1 | |
| SCHEMBL18085503 | 0.80 | CA1 (0.54) | NCF1ALDH1A1HTTLMNACA1 | |
| SCHEMBL12449629 | 0.78 | — | — | |
| SCHEMBL10173819 | 0.78 | — | — | |
| SCHEMBL12085 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006776-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND MEDICAL USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |