Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.47 |
| ▸ | FEN1 | P39748 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.43 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27295442 | 0.86 | HSPB1 (0.56) | ALOX5APFEN1SLC22A12HSPB1PDE4B | |
| SCHEMBL31473415 | 0.86 | HSPB1 (0.56) | ALOX5APFEN1SLC22A12HSPB1PDE4B | |
| SCHEMBL753498 | 0.81 | SLC6A4 (0.50) | SLC22A12SLC6A4KCNH2SLC6A2CYP19A1 | |
| SCHEMBL3696686 | 0.80 | ALOX5AP (0.47) | ALOX5APFEN1L3MBTL1SLC22A12HSPB1 | |
| SCHEMBL27300363 | 0.80 | ALOX5AP (0.55) | ALOX5APFEN1SLC22A12HSPB1PDE4B | |
| SCHEMBL31473343 | 0.80 | KMT2A (0.60) | ALOX5APFEN1L3MBTL1SLC22A12HSPB1 | |
| SCHEMBL27295176 | 0.80 | KMT2A (0.60) | ALOX5APFEN1L3MBTL1SLC22A12HSPB1 | |
| SCHEMBL31399235 | 0.78 | MRGPRX4 (0.43) | SLC22A12SLC6A4KCNH2TMPRSS4CYP19A1 | |
| SCHEMBL26126058 | 0.78 | MRGPRX4 (0.43) | SLC22A12SLC6A4KCNH2TMPRSS4CYP19A1 | |
| SCHEMBL3131610 | 0.78 | MERTK (0.46) | SLC6A4KCNH2SLC6A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |