Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSPB1 | P04792 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4373767 | 0.98 | MEN1 (0.53) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL12967182 | 0.83 | L3MBTL1 (0.50) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL21906692 | 0.83 | L3MBTL1 (0.50) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4369957 | 0.81 | MAOB (0.47) | KDM4EMAOBRAB9A | |
| SCHEMBL4375086 | 0.79 | MEN1 (0.45) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL31132787 | 0.77 | MEN1 (0.64) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL21906498 | 0.77 | L3MBTL1 (0.44) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL4380974 | 0.77 | MEN1 (0.63) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL30744447 | 0.77 | MEN1 (0.63) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL18362140 | 0.75 | MEN1 (0.45) | MEN1KMT2AKDM4EL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |