Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 14/20 | 0.66 |
| ▸ | CDC25B | P30305 | 9/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CDC45 | O75419 | 1/20 | 0.47 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.47 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.46 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27311802 | 0.85 | OSBP (0.52) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL28487113 | 0.85 | OSBP (0.52) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL28484483 | 0.85 | OSBP (0.52) | CDC25ACDC25BNPC1L1 | |
| SCHEMBL27941246 | 0.83 | CYP2D6 (0.53) | CDC25ACDC25BCYP2D6CYP2C19SRD5A1 | |
| SCHEMBL28776585 | 0.83 | CYP2D6 (0.53) | CDC25ACDC25BCYP2D6CYP2C19SRD5A1 | |
| SCHEMBL28776586 | 0.83 | CYP2D6 (0.53) | CDC25ACDC25BCYP2D6CYP2C19SRD5A1 | |
| SCHEMBL12153482 | 0.80 | CDC25A (1.00) | CDC25ACDC25BCYP2D6CYP2C19INPP5D | |
| SCHEMBL9558404 | 0.80 | CDC25A (1.00) | CDC25ACDC25BCYP2D6CYP2C19INPP5D | |
| SCHEMBL9121941 | 0.80 | CDC25A (1.00) | CDC25ACDC25BCYP2D6CYP2C19INPP5D | |
| SCHEMBL27378877 | 0.76 | CDC25A (0.63) | CDC25ACDC25BCYP2D6CYP2C19SRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1031938-C | Process for the preparing substituted indene | HOFFMANN LA ROCHE (CH) | 1996-06-05 | — | — | CN | claimed |
| CN-1031938-C | Process for the preparing substituted indene | HOFFMANN LA ROCHE (CH) | 1996-06-05 | — | — | CN | disclosed |
| CN-1062342-A | The method of the indenes that preparation replaces | HOFFMANN LA ROCHE (CH) | 1992-07-01 | — | — | CN | disclosed |
| CN-1062342-A | The method of the indenes that preparation replaces | HOFFMANN LA ROCHE (CH) | 1992-07-01 | — | — | CN | disclosed |