Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12264367 | 0.86 | MEN1 (0.45) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL2792621 | 0.86 | PDE2A (0.45) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL530151 | 0.81 | HTT (0.42) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL26965631 | 0.80 | CYP1A2 (0.49) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL12238633 | 0.79 | PDE2A (0.41) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL22939210 | 0.78 | HTT (0.45) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL22155098 | 0.78 | HTT (0.40) | MEN1KMT2AHTTALDH1A1GAA | |
| SCHEMBL34471152 | 0.77 | KIF11 (0.42) | ARNR3C1PDE2A | |
| SCHEMBL3855932 | 0.76 | MEN1 (0.65) | MEN1KMT2ANPSR1TSHR | |
| SCHEMBL1626272 | 0.76 | AKR1C3 (0.63) | MEN1KMT2AHTTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1034497-C | Process for the preparation of aromatic aminoalcohol derivatives useful for the treatment of diabetes and obesity | SANKYO CO (JP) | 1997-04-09 | — | — | CN | disclosed |
| CN-1073428-A | Aromatic amino alcohol derivatives having anti-diabetic and anti-obesity properties, their preparation and their therapeutic use | SANKYO CO (JP) | 1993-06-23 | — | — | CN | disclosed |