⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27305297 | 0.79 | — | — | |
| SCHEMBL23055640 | 0.74 | — | — | |
| SCHEMBL12962278 | 0.69 | — | — | |
| SCHEMBL21660601 | 0.67 | — | — | |
| SCHEMBL12719068 | 0.66 | — | — | |
| SCHEMBL12656309 | 0.65 | TSHR (0.46) | — | |
| SCHEMBL23683787 | 0.61 | SETD7 (0.32) | — | |
| SCHEMBL22415197 | 0.60 | — | — | |
| SCHEMBL13663705 | 0.59 | — | — | |
| SCHEMBL20124307 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023244815-A1 | MOLECULAR GLUE DEGRADERS AND METHODS OF USING THE SAME | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |