SCHEMBL27306322

CC[C@H](N)C(=O)NCCCCCC(=O)NC[C@H]1CC[C@H](C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)CC1

nearest known ligand 0.74

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	FOLH1	Q04609	15/20	0.74

▸	PLG	P00747	3/20	0.53

▸	PRSS1	P07477	3/20	0.53

▸	PRSS2	P07478	3/20	0.53

▸	PRSS3	P35030	3/20	0.53

▸	NMUR2	Q9GZQ4	2/20	0.46

▸	NMUR1	Q9HB89	2/20	0.46

▸	PLAU	P00749	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL27306091	0.94	FOLH1 (0.74)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL24374933	0.93	FOLH1 (0.81)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL31635857	0.93	FOLH1 (0.82)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL27304711	0.92	FOLH1 (0.77)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL21310703	0.91	FOLH1 (0.82)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL21310479	0.89	FOLH1 (0.80)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883225	0.89	FOLH1 (0.82)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883382	0.88	FOLH1 (0.79)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL22883383	0.88	FOLH1 (0.79)	FOLH1PLGPRSS1PRSS2PRSS3
SCHEMBL17706000	0.88	FOLH1 (0.81)	FOLH1PLGPRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2024028258-A1	CONJUGATES OF PSMA-BINDING MOIETIES WITH CYTOTOXIC AGENTS	PHILOCHEM AG (CH)	2024-02-08	—	—	WO	disclosed