Exifone

Exifone

SCHEMBL273096

O=C(c1cc(O)c(O)c(O)c1)c1ccc(O)c(O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 1/20 1.00
SELL P14151 2/20 0.54
SELP P16109 2/20 0.54
KDM4E B2RXH2 5/20 0.51
ALDH1A1 P00352 4/20 0.51
MAPT P10636 4/20 0.51
HPGD P15428 3/20 0.51
HSD17B10 Q99714 3/20 0.51
RECQL P46063 3/20 0.51
ALOX15 P16050 2/20 0.51
MEN1 O00255 1/20 0.50
ALOX12 P18054 1/20 0.50
KMT2A Q03164 1/20 0.50
FASN P49327 1/20 0.48
LMNA P02545 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
FUT7 Q11130 2/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Exifone SCHEMBL29375026 1.00 HDAC1 (1.00) HDAC1SELLSELPKDM4EALDH1A1
Exifone SCHEMBL27795679 0.98 HDAC1 (0.96) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL6847401 0.91 HDAC1 (0.84) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL30669853 0.91 HDAC1 (0.84) HDAC1SELLSELPKDM4EALDH1A1
Exifone SCHEMBL18993025 0.89 HDAC1 (0.80) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL19003430 0.89 HDAC1 (0.79) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL19763340 0.86 HDAC1 (0.76) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL19003428 0.86 HDAC1 (0.76) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL5703332 0.86 HDAC1 (0.75) HDAC1SELLSELPKDM4EALDH1A1
SCHEMBL30595472 0.86 HDAC1 (0.75) HDAC1SELLSELPKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4525870-A1 METHODS OF TREATING CUSHING'S SYNDROME AND LIVER DISORDERS, AND OF REDUCING LIVER TOXICITY OF OTHER DRUGS ADMINISTERED TO A PATIENT Corcept Therapeutics Incorporated (US) 2025-03-26 EP claimed
US-20240245659-A1 Methods of Treating Cushing's Syndrome and Liver Disorders, and of Reducing Liver Toxicity of Other Drugs Administered to a Patient CORCEPT THERAPEUTICS INCORPORATED (US) 2024-07-25 US claimed
CN-112731765-B Fluorine-containing resin composition, preparation method thereof and preparation method of cured film containing fluorine-containing resin composition 西安瑞联新材料股份有限公司 2024-03-26 CN claimed
EP-4317576-A1 FIBER-TREATING AGENT Kao Corporation (JP) 2024-02-07 EP claimed
US-20230372312-A1 Methods of Treating Cushing's syndrome and Liver Disorders, and of Reducing Liver Toxicity of Other Drugs Administered to a Patient CORCEPT THERAPEUTICS INCORPORATED (US) 2023-11-23 US claimed
WO-2023225282-A1 METHODS OF TREATING CUSHING'S SYNDROME AND LIVER DISORDERS, AND OF REDUCING LIVER TOXICITY OF OTHER DRUGS ADMINISTERED TO A PATIENT CORCEPT THERAPEUTICS INCORPORATED (US) 2023-11-23 WO claimed
US-20230194984-A1 FLUORINE-CONTAINING RESIN COMPOSITION AND PREPARATION METHOD THEREOF, AND PREPARATION METHOD OF CURED FILM CONTAINING SAME XI'AN MANARECO NEW MATERIALS CO., LTD. (CN) 2023-06-22 US claimed
EP-4193221-A1 SOLUBLE POLYIMIDES AND DIIMIDES FOR SPIN-ON CARBON APPLICATIONS Brewer Science Inc. (US) 2023-06-14 EP claimed
CN-116018380-A Soluble polyimides and imides for spin-on carbon applications 布鲁尔科技公司 2023-04-25 CN claimed
WO-2022210993-A1 FIBER-TREATING AGENT 花王株式会社 2022-10-06 WO claimed
EP-0651893-A1 HEXAHYDROXYBENZOPHENONE SULFONATE ESTERS OF DIAZONAPHTHOQUINONE SENSITIZERS AND POSITIVE PHOTORESISTS EMPLOYING SAME HOECHST CELANESE CORPORATION (US) 1995-05-10 EP claimed
US-5395728-A Containing alkali soluble novolak resin; improved heat resistance without sacrificing other propertes CLARIANT FINANCE (BVI) LIMITED (VG) 1995-03-07 US claimed
US-5294521-A Forming patterns on semiconductor wafers HOECHST CELANESE CORPORATION (US) 1994-03-15 US claimed
WO-1994002885-A1 HEXAHYDROXYBENZOPHENONE SULFONATE ESTERS OF DIAZONAPHTHOQUINONE SENSITIZERS AND POSITIVE PHOTORESISTS EMPLOYING SAME HOECHST CELANESE CORPORATION (US) 1994-02-03 WO claimed
US-5283324-A Reacting phenol compound and quinone diazide sulfonyl halide in solvent mixtures of different dielectric constants SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-02-01 US claimed
US-5206348-A Thermostability, high speed, heat resistance MORTON INTERNATIONAL, INC. (US) 1993-04-27 US claimed
EP-0275970-B1 POSITIVE-WORKING PHOTORESIST COMPOSITION FUJI PHOTO FILM CO., LTD. (JP) 1993-03-24 EP claimed
EP-0315964-B1 A NOVEL PHARMACEUTICAL COMPOSITION COMPRISING EXIFONE AND WATER-SOLUBLE POLYMER Laboratoires Pharmascience (FR) 1993-01-07 EP claimed
US-5093372-A Used in treatment of dementia, improved solubility, absorption cellulose ethers FUJISAWA PHARMACEUTICAL CO. INC. (JP) 1992-03-03 US claimed
EP-0315964-A1 A novel pharmaceutical composition comprising exifone and water-soluble polymer Laboratoires Pharmascience (FR) 1989-05-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245659-A1 Methods of Treating Cushing's Syndrome and Liver Disorders, and of Reducing Liver Toxicity of Other Drugs Administered to a Patient CYP3A43, NR3C2, CYP3A5 HDAC1 408/4885SELL 2891/4885SELP 2985/4885
US-20230372312-A1 Methods of Treating Cushing's syndrome and Liver Disorders, and of Reducing Liver Toxicity of Other Drugs Administered to a Patient CYP3A43, NR3C2, CYP3A5 HDAC1 408/4885SELL 2891/4885SELP 2985/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.