⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL454777 | 0.77 | — | — | |
| SCHEMBL29937226 | 0.77 | — | — | |
| SCHEMBL29765248 | 0.72 | THRB (0.50) | — | |
| SCHEMBL30782966 | 0.72 | THRB (0.50) | — | |
| SCHEMBL31490901 | 0.67 | — | — | |
| SCHEMBL1101395 | 0.67 | — | — | |
| SCHEMBL7415141 | 0.67 | — | — | |
| SCHEMBL8755245 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL6437470 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL6439762 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432995-B1 | — | — | None | — | — | US | claimed |
| US-6432995-B2 | INHIBIT THE RELEASE OF INFLAMMATORY CYTOKINES SUCH AS INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR FROM CELLS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-08-13 | — | — | US | claimed |
| EP-0214093-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | claimed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | claimed |
| US-4785002-A | Imidazo-pyrrolo-pyridines useful as fungicidal and growth-regulating agents | BAYER AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | claimed |
| US-8772313-B2 | Benzenesulfonyl or sulfonamide compounds suitable for treating disorders that respond to the modulation of the serotonin 5-HT6 receptor | ABBOTT LABORATORIES (US) | 2014-07-08 | — | — | US | disclosed |
| EP-1767564-B2 | POLYMER, A METHOD FOR PRODUCING THE POLYMER, AND A CEMENT ADMIXTURE USING THE SAME | NIPPON CATALYTIC CHEM IND (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-20120129883-A1 | BENZENESULFONYL OR SULFONAMIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO THE MODULATION OFTHE SEROTONIN 5-HT6 RECEPTOR | ABBOTT LABORATORIES (US) | 2012-05-24 | — | — | US | disclosed |
| WO-2012059431-A1 | BENZENESULFONYL OR SULFONAMIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO THE MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2012-05-10 | — | — | WO | disclosed |
| US-20100105636-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-1767564-B1 | Polymer, a method for producing the polymer, and a cement admixture using the same | NIPPON CATALYTIC CHEM IND (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20070129335-A1 | T-type calcium channel blocker | NISSAN CHEMICAL INDUSTRIES, LTD (JP) | 2007-06-07 | — | — | US | disclosed |
| EP-0382687-A2 | Benzofused-N-containing heterocycle derivatives | BOEHRINGER INGELHEIM ITALIA S.p.A. (IT) | 1990-08-16 | — | — | EP | disclosed |
| EP-0369385-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-05-23 | — | — | EP | disclosed |
| EP-0344519-A1 | Substituted 4-(quinolin-2-yl-methoxy)phenyl-acetic-acid derivatives | BAYER AG (DE) | 1989-12-06 | — | — | EP | disclosed |
| EP-0325130-A2 | Substituted pyridines | BAYER AG (DE) | 1989-07-26 | — | — | EP | disclosed |
| EP-0317845-A2 | Substituted hydroxyl amines | BAYER AG (DE) | 1989-05-31 | — | — | EP | disclosed |
| EP-0272534-A2 | 8-substituted 2-aminotetralins | BAYER AG (DE) | 1988-06-29 | — | — | EP | disclosed |
| EP-0253321-A2 | Benzenesulfonamido-indanyl-compounds, medicines containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-01-20 | — | — | EP | disclosed |
| EP-0058779-B1 | CARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS MEDICINES | Dr. Karl Thomae GmbH (DE) | 1984-09-19 | — | — | EP | disclosed |