Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | IDH1 | O75874 | 12/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.41 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | IDH2 | P48735 | 4/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL508376 | 0.83 | HCAR3 (0.53) | CYP11B1CYP11B2HCAR3 | |
| SCHEMBL14147328 | 0.78 | CYP11B1 (0.47) | CYP11B1CYP11B2HCAR3CCNT1 | |
| SCHEMBL31473372 | 0.73 | CCR6 (0.52) | — | |
| SCHEMBL27296081 | 0.73 | CCR6 (0.52) | — | |
| SCHEMBL27310330 | 0.73 | NAMPT (0.44) | CYP11B1CYP11B2IDH1HCAR3IDH2 | |
| SCHEMBL31127024 | 0.73 | IDH1 (0.43) | IDH1CCNT1IDH2 | |
| SCHEMBL21143821 | 0.73 | IDH1 (0.43) | IDH1CCNT1IDH2 | |
| SCHEMBL31591606 | 0.72 | LOX (0.43) | — | |
| SCHEMBL4342306 | 0.72 | LOX (0.43) | — | |
| SCHEMBL24415724 | 0.71 | CYP11B1 (0.58) | CYP11B1CYP11B2HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024029489-A1 | KIT INHIBITORS, COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | MODULUS DISCOVERY, INC. (JP) | 2024-02-08 | — | — | WO | disclosed |