SCHEMBL27312416

SCHEMBL27312416

N#CNC(=N)SCc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP2D6 P10635 2/20 0.54
CYP2C9 P11712 2/20 0.54
CYP2C19 P33261 2/20 0.54
IDO1 P14902 5/20 0.50
NOS1 P29475 2/20 0.50
NOS3 P29474 1/20 0.50
NOS2 P35228 1/20 0.50
CRHBP P24387 1/20 0.49
CRHR2 Q13324 1/20 0.49
CA12 O43570 1/20 0.43
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA9 Q16790 1/20 0.43
MAPT P10636 2/20 0.42
LMNA P02545 2/20 0.40
HTT P42858 2/20 0.40
USP2 O75604 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29001972 0.80 GAA (0.63) GAACYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL11064823 0.75 IDO1 (0.55) GAAIDO1NOS1NOS3NOS2
SCHEMBL7785354 0.73 IDO1 (0.53) GAAIDO1NOS1NOS3NOS2
Benzyl Carbamimidothioate SCHEMBL27476627 0.73 IDO1 (0.84) IDO1NOS1NOS3NOS2SLC11A2
SCHEMBL4917129 0.73 CYP1A2 (0.42) GAACYP1A2CYP2D6CYP2C9CYP2C19
Bromide SCHEMBL4921073 0.73 IDO1 (0.62) GAAIDO1NOS1NOS3NOS2
SCHEMBL13256326 0.72 IDO1 (0.52) GAAIDO1NOS1NOS3NOS2
Benzylamidinoisothiourea SCHEMBL13460125 0.72 IDO1 (0.62) GAAIDO1NOS1NOS3NOS2
SCHEMBL11506070 0.72 GAA (0.65) GAACYP1A2CYP2D6CYP2C9CYP2C19
Benzylamidinoisothiourea SCHEMBL10658003 0.70 IDO1 (0.63) GAAIDO1NOS1NOS3NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1033624-A High-potency sweetener NUTRASWEET CO (US) 1989-07-05 CN disclosed