Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 4/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312320 | 0.83 | PDE4A (0.41) | GRM2PDE4A | |
| SCHEMBL27312845 | 0.82 | — | — | |
| SCHEMBL27312487 | 0.81 | PDE4A (0.47) | GRM2PDE4A | |
| SCHEMBL27312168 | 0.70 | PDE4A (0.55) | PDE4A | |
| SCHEMBL27313430 | 0.69 | PDE4A (0.48) | PDE4A | |
| SCHEMBL30954519 | 0.67 | PDE4A (0.34) | GRM2PDE4A | |
| SCHEMBL30954493 | 0.65 | MAPK1 (0.31) | — | |
| SCHEMBL27312844 | 0.65 | MAPK1 (0.31) | — | |
| SCHEMBL30954525 | 0.65 | MAPK1 (0.31) | — | |
| SCHEMBL27312767 | 0.65 | MAPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |