Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 17/20 | 0.47 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27312320 | 0.93 | PDE4A (0.41) | PDE4AGRM2PDE4CPDE4D | |
| SCHEMBL27309872 | 0.84 | PDE4A (0.53) | PDE4AGRM2PDE4CPDE4D | |
| SCHEMBL27312168 | 0.81 | PDE4A (0.55) | PDE4APDE4CPDE4D | |
| SCHEMBL27312482 | 0.81 | GRM2 (0.35) | PDE4AGRM2 | |
| SCHEMBL30954519 | 0.77 | PDE4A (0.34) | PDE4AGRM2PDE4CPDE4D | |
| SCHEMBL27312848 | 0.77 | PDE4A (0.34) | PDE4AGRM2PDE4CPDE4D | |
| SCHEMBL27309870 | 0.75 | PDE4A (0.42) | PDE4APDE4CPDE4D | |
| SCHEMBL27312687 | 0.74 | PDE4A (0.52) | PDE4APDE4CPDE4D | |
| SCHEMBL27309860 | 0.71 | PDE4A (0.70) | PDE4APDE4CPDE4D | |
| SCHEMBL27309978 | 0.71 | PDE4A (0.46) | PDE4AGRM2PDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024118524-A1 | AZAINDOLE COMPOUNDS AND THEIR USE AS PHOSPHODIESTERASE INHIBITORS | CEREVEL THERAPEUTICS, LLC (US) | 2024-06-06 | — | — | WO | disclosed |