Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL355839 | 0.80 | TDP1 (0.53) | LMNAMAPTALDH1A1SCDPTGS2 | |
| SCHEMBL1939686 | 0.75 | LMNA (0.50) | LMNAMAPTALDH1A1PTGS2PTGDR2 | |
| SCHEMBL13232783 | 0.74 | LMNA (0.40) | LMNAMAPTALDH1A1SCDPTGS2 | |
| SCHEMBL755309 | 0.73 | LMNA (0.60) | LMNAMAPTALDH1A1PTGS2MEN1 | |
| SCHEMBL1577287 | 0.72 | LMNA (0.55) | LMNAMAPTALDH1A1PTGS2PDK1 | |
| SCHEMBL21491187 | 0.71 | LMNA (0.54) | LMNAMAPTALDH1A1PTGS2MEN1 | |
| SCHEMBL30540158 | 0.71 | LMNA (0.54) | LMNAMAPTALDH1A1PTGS2MEN1 | |
| SCHEMBL27313304 | 0.71 | LMNA (0.40) | LMNAMAPTALDH1A1PTGS2FAAH | |
| SCHEMBL27691405 | 0.71 | RECQL (0.39) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7946495 | 0.71 | LMNA (0.49) | LMNAMAPTALDH1A1PTGS2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066439-C | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGROCHIMIE (GB) | 2001-05-30 | — | — | CN | disclosed |
| CN-1141294-A | Method for prepn. of isoxazoles herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-01-29 | — | — | CN | disclosed |
| CN-1050188-A | ISOXAZOLES HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1991-03-27 | — | — | CN | disclosed |