SCHEMBL27313616

SCHEMBL27313616

Cc1c(CO)cccc1Cc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.58
CD274 Q9NZQ7 1/20 0.58
BCL2 P10415 1/20 0.45
BCL2L1 Q07817 1/20 0.45
TSHR P16473 2/20 0.44
HTR2A P28223 1/20 0.42
CALM1 P0DP23 1/20 0.42
CNR2 P34972 1/20 0.42
GPR55 Q9Y2T6 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C19 P33261 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7861886 0.89 CALM1 (0.52) PDCD1CD274BCL2BCL2L1TSHR
SCHEMBL6424004 0.82 PDCD1 (0.64) PDCD1CD274
SCHEMBL6546124 0.82 TP53 (0.46) BCL2BCL2L1HTR2ACALM1CNR2
SCHEMBL1276090 0.81 CALM1 (0.48) BCL2BCL2L1TSHRHTR2ACALM1
SCHEMBL1773099 0.81 HTR2A (0.56) BCL2BCL2L1TSHRHTR2ACALM1
SCHEMBL5648473 0.80 BCL2 (0.55) BCL2BCL2L1CNR2GPR55CYP3A4
SCHEMBL10703986 0.79 PDCD1 (0.44) PDCD1CD274BCL2BCL2L1TSHR
Ammonia Solution, Strong SCHEMBL27502158 0.79 CALM1 (0.46) BCL2BCL2L1TSHRHTR2ACALM1
SCHEMBL9181341 0.78 CD274 (0.67) PDCD1CD274HTR2A
SCHEMBL8098213 0.78 CALM1 (0.55) BCL2BCL2L1HTR2ACALM1CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108218696-A A kind of production technology of Biphenthrin 江苏优嘉植物保护有限公司 2018-06-29 CN disclosed
CN-1033798-A New imidate insecticides ICI AMERICA INC (US) 1989-07-12 CN disclosed