Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17617120 | 0.90 | ALDH1A1 (0.53) | ALDH1A1RECQLMMP8PTPN1PTPRC | |
| SCHEMBL28767943 | 0.88 | EGFR (0.38) | ALDH1A1RECQLMMP8PTPN1PTPRC | |
| Ammonia Solution, Strong SCHEMBL27875656 | 0.83 | ALDH1A1 (0.56) | ALDH1A1PTPN1PTPRCKMT2AMEN1 | |
| SCHEMBL5436754 | 0.83 | ALDH1A1 (0.55) | ALDH1A1PTPN1PTPRCKMT2AMEN1 | |
| SCHEMBL25576433 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL19690610 | 0.79 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL11705180 | 0.79 | ALDH1A1 (0.59) | ALDH1A1RECQLMMP8KMT2AMEN1 | |
| SCHEMBL18085412 | 0.78 | ALDH1A1 (0.52) | ALDH1A1RECQLMMP8L3MBTL1TDP1 | |
| SCHEMBL28300052 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1MAPK1L3MBTL1 | |
| SCHEMBL28769815 | 0.78 | ALDH1A1 (0.50) | ALDH1A1RECQLMMP8PTPN1PTPRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101742909-B | Use of compounds having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions | COMMISSARIAT ENERGIE ATOMIQUE | 2014-07-09 | — | — | CN | disclosed |
| CN-101742909-A | Have purposes and weed killer herbicide and the algaecide composition of the compound of single galactosyl DG synthase inhibitory activity as weed killer herbicide or algicide | CENTRE NAT RECH SCIENT | 2010-06-16 | — | — | CN | disclosed |
| CN-1027695-C | Heterocyclic-NMDA antagonists | MERRELL DOW PHARMA (US) | 1995-02-22 | — | — | CN | disclosed |
| CN-1056499-A | HETEROCYCLIC-NMDA ANTAGONISTS | MERRELL DOW PHARMA (US) | 1991-11-27 | — | — | CN | disclosed |