Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.36 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.36 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7218991 | 0.72 | NR4A1 (0.71) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL29494693 | 0.72 | NR4A1 (0.71) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL27523850 | 0.71 | HPRT1 (0.41) | HPRT1ALDH1A1MAPTMEN1LMNA | |
| SCHEMBL15903547 | 0.71 | HPRT1 (0.44) | NR4A1NR4A2NR4A3HPRT1SOS1 | |
| SCHEMBL15903797 | 0.69 | HPRT1 (0.41) | HPRT1SOS1ALDH1A1MAPTMEN1 | |
| SCHEMBL31464018 | 0.69 | ALDH1A1 (0.46) | HPRT1SOS1ALDH1A1MAPTMEN1 | |
| SCHEMBL28513228 | 0.68 | NR4A1 (0.55) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL548063 | 0.68 | NR4A1 (0.55) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL14211980 | 0.67 | NR4A1 (0.64) | NR4A1NR4A2NR4A3MMP3HDAC8 | |
| SCHEMBL1314383 | 0.67 | HPRT1 (0.56) | NR4A1NR4A2NR4A3MMP3HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1030986-C | Pyrrolopyrazine | HOFFMANN LA ROCHE (CH) | 1996-02-14 | — | — | CN | disclosed |