Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 10/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5960895 | 0.86 | KDM1A (0.42) | KDM1AMAOB | |
| SCHEMBL29453777 | 0.86 | KDM1A (0.42) | KDM1AMAOB | |
| SCHEMBL302419 | 0.86 | KDM1A (0.42) | KDM1AMAOB | |
| SCHEMBL2146984 | 0.86 | KDM1A (0.42) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL27310401 | 0.85 | KDM1A (0.41) | KDM1AMAOB | |
| Hydrochloric Acid SCHEMBL1970466 | 0.85 | KDM1A (0.41) | KDM1AMAOB | |
| SCHEMBL301710 | 0.82 | MAOB (0.43) | HDAC9KDM1AMAOBIDO1TDO2 | |
| SCHEMBL2325227 | 0.78 | KDM1A (0.47) | KDM1A | |
| SCHEMBL4737865 | 0.73 | HDAC9 (0.44) | KIF11HDAC9KDM1AMAOBHCAR2 | |
| SCHEMBL4735703 | 0.73 | HDAC9 (0.44) | KIF11HDAC9KDM1AMAOBHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4719474-A1 | METHOD OF TREATING FIBROTIC-RELATED CONDITION | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) | 2026-04-08 | — | — | EP | disclosed |
| WO-2024252394-A1 | METHOD OF TREATING FIBROTIC-RELATED CONDITION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2024-12-12 | — | — | WO | disclosed |
| CN-1031995-C | R-enantiomers of N-propargyl-1-aminoindan compounds, their preparation and pharmaceutical compositions containing them | ORVET BV (NL) | 1996-06-12 | — | — | CN | disclosed |