Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 11/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16814173 | 0.79 | ALDH1A1 (0.44) | BTKSLC6A3HCAR2ALDH1A1KDM4E | |
| SCHEMBL4282035 | 0.79 | HCAR2 (0.57) | BTKSLC6A3HCAR2ALDH1A1KDM4E | |
| SCHEMBL18183949 | 0.78 | BTK (0.39) | BTKSLC6A3HCAR2ALDH1A1KDM4E | |
| SCHEMBL17936109 | 0.78 | ALDH1A1 (0.38) | BTKSLC6A3HCAR2ALDH1A1KDM4E | |
| SCHEMBL18997957 | 0.76 | HCAR2 (0.62) | HCAR2RAB9ACCNE1CDK2CDK5 | |
| SCHEMBL24415622 | 0.75 | HDAC3 (0.36) | BTKSLC6A3HCAR2ALDH1A1RAB9A | |
| SCHEMBL12868672 | 0.75 | HPGD (0.41) | BTKHCAR2ALDH1A1KDM4ERAB9A | |
| SCHEMBL21133751 | 0.75 | POLB (0.46) | BTKALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL4276371 | 0.75 | CDC7 (0.55) | BTKALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL27395757 | 0.74 | ALDH1A1 (0.38) | HCAR2ALDH1A1RAB9ACCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026481-A2 | CDK2 INHIBITORS AND METHODS OF USING THE SAME | CEDILLA THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |