Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27309743 | 0.89 | PIN1 (0.46) | PIN1POLBNPSR1ALDH1A1RECQL | |
| SCHEMBL1455681 | 0.87 | PIN1 (0.50) | PIN1POLBNPSR1ALDH1A1RECQL | |
| SCHEMBL27579783 | 0.85 | PIN1 (0.49) | PIN1POLBNPSR1ALDH1A1RECQL | |
| Hydrochloric Acid SCHEMBL1977471 | 0.85 | PIN1 (0.49) | PIN1POLBNPSR1ALDH1A1RECQL | |
| SCHEMBL12537092 | 0.84 | MAPT (0.46) | PIN1POLBNPSR1ALDH1A1RECQL | |
| SCHEMBL31174124 | 0.83 | RECQL (0.55) | PIN1CYP2C19HIF1APOLBNPSR1 | |
| SCHEMBL27533200 | 0.83 | TDP1 (0.49) | CYP2C19HIF1AALDH1A1TSHRMAPT | |
| SCHEMBL3617440 | 0.81 | HTT (0.50) | PIN1POLBNPSR1ALDH1A1RECQL | |
| SCHEMBL3617442 | 0.81 | HTT (0.50) | PIN1POLBNPSR1ALDH1A1RECQL | |
| SCHEMBL28308257 | 0.81 | PIN1 (0.45) | PIN1POLBNPSR1ALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1050839-C | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 2000-03-29 | — | — | CN | disclosed |
| CN-1106007-A | Novel sulfonylamino pyrimidines | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |