SCHEMBL27317399

SCHEMBL27317399

CNCCCCNCCNC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
TSHR P16473 2/20 0.47
ALDH1A1 P00352 1/20 0.47
PAOX Q6QHF9 1/20 0.46
CYP2C19 P33261 3/20 0.45
CYP1A2 P05177 3/20 0.45
CASP2 P42575 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
CA12 O43570 2/20 0.40
F13A1 P00488 2/20 0.40
CA2 P00918 2/20 0.40
ALOX15 P16050 2/20 0.40
CA4 P22748 2/20 0.40
CA6 P23280 2/20 0.40
CA5A P35218 2/20 0.40
THPO P40225 2/20 0.40
CA7 P43166 2/20 0.40
CA9 Q16790 2/20 0.40
CA14 Q9ULX7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3020474 0.93 CYP2C19 (0.47) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL24415673 0.93 CYP2C19 (0.47) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL18870232 0.93 EPHX1 (0.50) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL5932994 0.93 EPHX1 (0.56) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL9971087 0.90 CYP2C19 (0.56) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL7521377 0.90 EPHX1 (0.61) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL15900056 0.90 EPHX1 (0.61) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL7511396 0.90 CYP2C19 (0.56) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL12085580 0.90 CYP2C19 (0.50) EPHX1TSHRALDH1A1PAOXCYP2C19
SCHEMBL18608790 0.90 CYP2C19 (0.50) EPHX1TSHRALDH1A1PAOXCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed
WO-2024052702-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed