Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.44 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 3/20 | 0.40 |
| ▸ | CA6 | P23280 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27317399 | 0.93 | EPHX1 (0.50) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL7521377 | 0.90 | EPHX1 (0.61) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL18608790 | 0.90 | CYP2C19 (0.50) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL15900056 | 0.90 | EPHX1 (0.61) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL24042526 | 0.89 | EPHX1 (0.70) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL6892698 | 0.89 | EPHX1 (0.70) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL6888368 | 0.89 | EPHX1 (0.70) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL11974145 | 0.89 | EPHX1 (0.70) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL820309 | 0.89 | EPHX1 (0.70) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL17480037 | 0.89 | EPHX1 (0.70) | EPHX1TSHRALDH1A1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137380-A1 | IONIC LIQUID FILMS WITH MULTIPLE FUNCTIONALITIES FOR SURFACE MODIFICATION OF BIOMEDICAL ALLOYS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137380-A1 | IONIC LIQUID FILMS WITH MULTIPLE FUNCTIONALITIES FOR SURFACE MODIFICATION OF BIOMEDICAL ALLOYS | MIF, STAT1, IRF3 | EPHX1 4109/4885TSHR 4226/4885ALDH1A1 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.