Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 4/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.41 |
| ▸ | CTSC | P53634 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273833 | 1.00 | L3MBTL1 (0.61) | L3MBTL1SMYD3DPP4DPP8DPP9 | |
| SCHEMBL7267347 | 1.00 | L3MBTL1 (0.61) | L3MBTL1SMYD3DPP4DPP8DPP9 | |
| SCHEMBL6533367 | 1.00 | L3MBTL1 (0.61) | L3MBTL1SMYD3DPP4DPP8DPP9 | |
| SCHEMBL18823908 | 0.84 | L3MBTL1 (0.62) | L3MBTL1ALDH1A1EPHX2HDAC8CYP1A2 | |
| SCHEMBL23001643 | 0.82 | L3MBTL1 (0.43) | L3MBTL1SMYD3DPP4DPP8DPP9 | |
| SCHEMBL27392159 | 0.81 | L3MBTL1 (0.61) | L3MBTL1CTSCALDH1A1EPHX2HDAC8 | |
| SCHEMBL27418097 | 0.80 | L3MBTL1 (0.59) | L3MBTL1SMYD3CTSCALDH1A1EPHX2 | |
| Hydrochloric Acid SCHEMBL7306318 | 0.80 | L3MBTL1 (0.59) | L3MBTL1CTSCALDH1A1EPHX2HDAC8 | |
| Hydrochloric Acid SCHEMBL7306328 | 0.80 | L3MBTL1 (0.59) | L3MBTL1CTSCALDH1A1EPHX2HDAC8 | |
| SCHEMBL27415878 | 0.80 | L3MBTL1 (0.59) | L3MBTL1CTSCALDH1A1EPHX2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632255-A1 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | disclosed |
| WO-2012058203-A1 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | disclosed |