Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15370119 | 1.00 | CYP3A4 (0.34) | CYP3A4ALOX15 | |
| SCHEMBL2731988 | 1.00 | CYP3A4 (0.34) | CYP3A4ALOX15 | |
| SCHEMBL15363844 | 0.98 | CYP3A4 (0.33) | CYP3A4ALOX15 | |
| SCHEMBL15370116 | 0.88 | CYP3A4 (0.36) | CYP3A4ALOX15 | |
| SCHEMBL11300845 | 0.86 | CYP3A4 (0.35) | CYP3A4ALOX15 | |
| SCHEMBL15363841 | 0.82 | — | — | |
| SCHEMBL15363842 | 0.82 | — | — | |
| SCHEMBL15407395 | 0.79 | CYP3A4 (0.32) | CYP3A4ALOX15 | |
| SCHEMBL11892640 | 0.79 | CYP3A4 (0.32) | CYP3A4ALOX15 | |
| SCHEMBL2733397 | 0.79 | CYP3A4 (0.43) | CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632255-A1 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2013-09-04 | — | — | EP | claimed |
| WO-2012058203-A1 | DIAZENIUMDIOLATE HETEROCYCLIC DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2012-05-03 | — | — | WO | claimed |