Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.58 |
| ▸ | CSNK2A1 | P68400 | 14/20 | 0.56 |
| ▸ | CSNK2A2 | P19784 | 12/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 11/20 | 0.54 |
| ▸ | LATS1 | O95835 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.50 |
| ▸ | CSNK2A3 | Q8NEV1 | 4/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30803552 | 1.00 | BRD4 (0.58) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL30803487 | 0.95 | BRD4 (0.53) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL30803509 | 0.94 | LATS1 (0.60) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL27319841 | 0.94 | LATS1 (0.60) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL30803611 | 0.94 | CSNK2A1 (0.52) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL30803542 | 0.92 | CSNK2A1 (0.53) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL27320168 | 0.92 | CSNK2A1 (0.65) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL30803489 | 0.92 | CSNK2A1 (0.65) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL25371719 | 0.92 | CSNK2A1 (0.56) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 | |
| SCHEMBL30803554 | 0.92 | LATS1 (0.54) | BRD4CSNK2A1CSNK2A2CSNK2BLATS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052692-A1 | NOVEL COMPOUNDS AS CK2 INHIBITORS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |