SCHEMBL30803554

SCHEMBL30803554

COC(=O)c1ccc2c(c1)nc(NCCNC(=O)CCCNC(=O)OC(C)(C)C)c1ccncc12

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LATS1 O95835 1/20 0.54
CSNK2A1 P68400 16/20 0.51
BRD4 O60885 2/20 0.51
CSNK2A2 P19784 14/20 0.50
CSNK2B P67870 13/20 0.50
CSNK2A3 Q8NEV1 6/20 0.50
HDAC1 Q13547 4/20 0.50
HDAC6 Q9UBN7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803542 0.97 CSNK2A1 (0.53) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL30803611 0.94 CSNK2A1 (0.52) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL30803487 0.93 BRD4 (0.53) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL27319841 0.93 LATS1 (0.60) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL30803509 0.93 LATS1 (0.60) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL27320162 0.92 BRD4 (0.58) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL30803552 0.92 BRD4 (0.58) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL30803505 0.87 CSNK2A1 (0.57) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL25371719 0.87 CSNK2A1 (0.56) LATS1CSNK2A1BRD4CSNK2A2CSNK2B
SCHEMBL30803559 0.86 CSNK2A1 (0.55) LATS1CSNK2A1BRD4CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTPR LTD (GB) 2026-03-12 US disclosed
EP-4584267-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS Cambridge Enterprise Limited (GB) 2025-07-16 EP disclosed
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260070901-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CSNK1A1, CSNK2A3, CSNK1G1 LATS1 589/4885CSNK2A1 5/4885BRD4 160/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.