Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7669379 | 0.91 | HTR3A (0.52) | KCNH2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7669376 | 0.91 | HTR3A (0.52) | KCNH2CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28298503 | 0.83 | HTR3A (0.45) | CHEK1CCNA2CDK2CCNA1HTR3A | |
| SCHEMBL18825946 | 0.80 | KDR (0.41) | DRD2DRD3HCAR2 | |
| SCHEMBL3089324 | 0.80 | — | — | |
| SCHEMBL9811537 | 0.79 | SLC18A3 (0.52) | HTR3AHCAR2HTR2C | |
| SCHEMBL146605 | 0.78 | KDR (0.43) | HCAR2 | |
| SCHEMBL31087550 | 0.78 | KDR (0.43) | HCAR2 | |
| SCHEMBL381572 | 0.72 | SLC18A3 (0.59) | DRD2DRD3KCNH2CYP2D6SLC6A2 | |
| SCHEMBL4280 | 0.72 | SLC18A3 (0.59) | DRD2DRD3KCNH2CYP2D6SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1045595-C | Process for the preparation of the intermediates used in the synthesis of 3-aminopiperidine derivatives | PFIZER (US) | 1999-10-13 | — | — | CN | disclosed |