SCHEMBL27320441

SCHEMBL27320441

NC(=O)c1cc(Cl)c(Cl)c(Cl)c1OCl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA5A P35218 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA13 Q8N1Q1 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
KMT2A Q03164 2/20 0.35
ATM Q13315 1/20 0.35
NNMT P40261 2/20 0.34
LMNA P02545 4/20 0.33
ALDH1A1 P00352 3/20 0.33
HTT P42858 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8647557 0.77 CYP3A4 (0.46) CA12CA1CA2CA3CA4
SCHEMBL8776820 0.74
SCHEMBL14776122 0.72 ALDH1A1 (0.46) NNMTLMNAALDH1A1HTTHPGD
SCHEMBL2502851 0.71 CA12 (0.48) CA12CA1CA2CA3CA4
SCHEMBL11479346 0.71 CA12 (0.59) CA12CA1CA2CA3CA4
SCHEMBL15568158 0.70 PPARG (0.48) KMT2ALMNAALDH1A1HTTMAPT
SCHEMBL658339 0.69 CA12 (0.40) CA12CA1CA2CA3CA4
SCHEMBL31124523 0.69 CA12 (0.63) CA12CA1CA2CA3CA4
SCHEMBL31124522 0.69 CA12 (0.63) CA12CA1CA2CA3CA4
SCHEMBL11735279 0.69 KMT2A (0.47) KMT2AATMLMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102145973-A Composite uncoupling agent CHINA PETROLEUM & CHEMICAL 2011-08-10 CN claimed
CN-102145972-A Method for reducing excess sludge of aerobic unit of sewage treatment system by activated sludge process CHINA PETROLEUM & CHEMICAL 2011-08-10 CN claimed
CN-101746887-B Compounded decoupling agent SINOPEC SHANGHAI PETROCHEMICAL 2011-06-15 CN claimed
CN-101746885-A Compound uncoupling agent SINOPEC SHANGHAI PETROCHEMICAL 2010-06-23 CN claimed
CN-101746886-A Uncoupler SINOPEC SHANGHAI PETROCHEMICAL 2010-06-23 CN claimed
CN-101746888-A Method for reducing excess sludge yield rate of aerobic unit for activated sludge and sewage treatment process SINOPEC SHANGHAI PETROCHEMICAL 2010-06-23 CN claimed
CN-101746889-A Method for reducing sludge of aerobic unit in activated sludge and sewage treatment process SINOPEC SHANGHAI PETROCHEMICAL 2010-06-23 CN claimed
CN-101746890-A Method for reducing excess sludge yield of aerobic unit in activated sludge and sewage treatment process SINOPEC SHANGHAI PETROCHEMICAL 2010-06-23 CN claimed
CN-101746887-A Compounded decoupling agent SINOPEC SHANGHAI PETROCHEMICAL 2010-06-23 CN claimed
CN-107500404-B Composite uncoupler for sludge reduction and preparation method thereof 沈阳建筑大学 2021-01-01 CN disclosed
CN-102145973-B Composite uncoupling agent CHINA PETROLEUM & CHEMICAL 2012-12-26 CN disclosed
CN-102145972-B Method for reducing excess sludge of aerobic unit of sewage treatment system by activated sludge process CHINA PETROLEUM & CHEMICAL 2012-12-26 CN disclosed
CN-102145972-B Method for reducing excess sludge of aerobic unit of sewage treatment system by activated sludge process CHINA PETROLEUM & CHEMICAL 2012-12-26 CN disclosed
CN-101076583-B Solid laundry detergents containing polyanionic ammonium surfactants UNILEVER NV 2011-08-31 CN disclosed
CN-1204506-A Oral compositions SUNSTAR INC (JP) 1999-01-13 CN disclosed
CN-1176594-A Method, composition and dentifrice system for protecting dental surfaces A M HOMOLA (US) 1998-03-18 CN disclosed
CN-1126432-A Oral compositions for treating plaque and gingivitis containing a noncationic antibacterial agent and a bicarbonate salt PROCTER & GAMBLE (US) 1996-07-10 CN disclosed
CN-1081366-A Antibacterial antiplaque oral composition COLGATE PALMOLIVE CO (US) 1994-02-02 CN disclosed
CN-1067068-A LIGHT DUTY LIQUID DETERGENT COMPOSITIONS COLGATE PALMOLIVE CO (US) 1992-12-16 CN disclosed
CN-1044047-A ANTIPLAQUE ANTIBACTERIAL ORAL COMPOSITION COLGATE PALMOLIVE CO (US) 1990-07-25 CN disclosed