Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 16/20 | 0.54 |
| ▸ | MTOR | P42345 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27318560 | 1.00 | PIK3C3 (0.54) | PIK3C3MTORLMNA | |
| SCHEMBL7767952 | 1.00 | PIK3C3 (0.54) | PIK3C3MTORLMNA | |
| SCHEMBL21256945 | 0.84 | PIK3C3 (0.50) | PIK3C3MTOR | |
| SCHEMBL26515061 | 0.84 | PIK3C3 (0.50) | PIK3C3MTOR | |
| SCHEMBL25222723 | 0.82 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL24681517 | 0.82 | MTOR (0.50) | PIK3C3MTOR | |
| SCHEMBL22296389 | 0.82 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL24681530 | 0.82 | MTOR (0.50) | PIK3C3MTOR | |
| SCHEMBL22296387 | 0.82 | PIK3C3 (0.49) | PIK3C3 | |
| SCHEMBL16611301 | 0.82 | PIK3C3 (0.49) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1049431-C | Morpholine and thiomorpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 2000-02-16 | — | — | CN | claimed |
| CN-113072460-B | Morpholine derivative oxidation ring-opening method and product thereof | 西南大学 | 2022-06-24 | — | — | CN | disclosed |
| CN-113072460-A | Morpholine derivative oxidation ring-opening method and product thereof | 西南大学 | 2021-07-06 | — | — | CN | disclosed |
| CN-1049431-C | Morpholine and thiomorpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 2000-02-16 | — | — | CN | disclosed |