Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.55 |
| ▸ | CFTR | P13569 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | HPGD | P15428 | 7/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | FADS1 | O60427 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10966054 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL27579657 | 0.85 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| Formic Acid SCHEMBL28840569 | 0.82 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL18319627 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL21847565 | 0.82 | MAPT (0.53) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL26800839 | 0.81 | ALDH1A1 (0.61) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL7093463 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL29568750 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL1207894 | 0.79 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CFTRKDM4EHPGD | |
| SCHEMBL16203311 | 0.78 | MAPT (0.65) | ALDH1A1HSD17B10CFTRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522657-B | STAT3/5 activation inhibitor | OTSUKA PHARMACEUTICAL CO.,LTD. (JP) | 2014-10-15 | — | — | CN | disclosed |
| CN-103224488-A | Heterocyclic compound or salt thereof | OTSUKA PHARMA CO LTD | 2013-07-31 | — | — | CN | disclosed |
| CN-1993339-B | Aromatic compound | OTSUKA PHARMA CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-101842367-A | Heterocyclic compounds and pharmaceutical compositions thereof | OTSUKA PHARMA CO LTD | 2010-09-22 | — | — | CN | disclosed |
| CN-101522657-A | STAT3/5 activation inhibitor | OTSUKA PHARMA CO LTD (JP) | 2009-09-02 | — | — | CN | disclosed |
| CN-1993339-A | Aromatic compound | OTSUKA PHARMA CO LTD (JP) | 2007-07-04 | — | — | CN | disclosed |
| CN-1053666-C | Benzoheterocyclic compounds | OTSUKA PHARMA CO LTD (JP) | 2000-06-21 | — | — | CN | disclosed |
| CN-1030237-A | BENZOHETEROCYCLIC COMPOUNDS | OTSUKA PHARMA CO LTD (JP) | 1989-01-11 | — | — | CN | disclosed |