Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.45 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | Q9HBH1 | 1/20 | 0.40 | |
| ▸ | NMT2 | O60551 | 2/20 | 0.39 |
| ▸ | NMT1 | P30419 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18105654 | 0.81 | GSR (0.44) | SIRT6SIRT1DPP8DPP9DPP7 | |
| SCHEMBL13218612 | 0.81 | GSR (0.44) | SIRT6SIRT1DPP8DPP9DPP7 | |
| SCHEMBL13067469 | 0.80 | FOLH1 (0.54) | SLC6A5CA1 | |
| SCHEMBL10046476 | 0.78 | TLR2 (0.70) | TLR2SIRT6SIRT1SLC6A5NMT2 | |
| SCHEMBL29893154 | 0.78 | DPP8 (0.49) | TLR2SIRT6SIRT1DPP8DPP9 | |
| SCHEMBL29805332 | 0.78 | DPP8 (0.49) | TLR2SIRT6SIRT1DPP8DPP9 | |
| SCHEMBL31325363 | 0.78 | DPP8 (0.49) | TLR2SIRT6SIRT1DPP8DPP9 | |
| SCHEMBL14426180 | 0.78 | TLR2 (0.46) | TLR2SIRT6SIRT1NMT2NMT1 | |
| SCHEMBL22519362 | 0.78 | TLR2 (0.46) | TLR2SIRT6SIRT1NMT2NMT1 | |
| SCHEMBL29462129 | 0.78 | DPP8 (0.49) | TLR2SIRT6SIRT1DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023100158-A9 | SUBSTRATES FOR IMAGING GLUCOCEREBROSIDASE ACTIVITY | SIMON FRASER UNIVERSITY (CA) | 2023-12-07 | — | — | WO | disclosed |