SCHEMBL29462129

SCHEMBL29462129

NCCCC[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CCCCN)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DPP8 Q6V1X1 2/20 0.49
DPP9 Q86TI2 2/20 0.49
DPP7 Q9UHL4 2/20 0.49
GSR P00390 1/20 0.47
GNAI3 P08754 1/20 0.45
GNAO1 P09471 1/20 0.45
GNAI1 P63096 1/20 0.45
NOD1 Q9Y239 1/20 0.44
DPP4 P27487 1/20 0.43
TLR2 O60603 1/20 0.43
MMP2 P08253 1/20 0.43
NPY4R P50391 3/20 0.42
NPY1R P25929 2/20 0.42
NPY2R P49146 2/20 0.42
NPY5R Q15761 2/20 0.42
SIRT6 Q8N6T7 1/20 0.41
SIRT1 Q96EB6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740503 1.00 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL29893154 1.00 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL29805332 1.00 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL31325363 1.00 DPP8 (0.49) DPP8DPP9DPP7GSRGNAI3
SCHEMBL7570529 0.97 DPP8 (0.51) DPP8DPP9DPP7GSRGNAI3
SCHEMBL27584028 0.95 DPP8 (0.50) DPP8DPP9DPP7GSRGNAI3
SCHEMBL27562795 0.95 DPP8 (0.50) DPP8DPP9DPP7GSRGNAI3
SCHEMBL30399386 0.93 NOD1 (0.45) DPP8DPP9DPP7GSRGNAI3
SCHEMBL27481469 0.91 DPP7 (0.50) DPP8DPP9DPP7GSRGNAI3
SCHEMBL27498622 0.91 DPP7 (0.50) DPP8DPP9DPP7GSRGNAI3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250206798-A1 INSULIN CONJUGATES SANOFI SA (FR) 2025-06-26 US disclosed
US-12195510-B2 Insulin conjugates SANOFI (FR) 2025-01-14 US disclosed
US-20220048968-A1 INSULIN CONJUGATES SANOFI (FR) 2022-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220048968-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R DPP8 818/4885DPP9 1115/4885DPP7 768/4885
US-12195510-B2 Insulin conjugates IAPP, INSR, IGF1R DPP8 818/4885DPP9 1115/4885DPP7 768/4885
US-20250206798-A1 INSULIN CONJUGATES IAPP, INSR, IGF1R DPP8 818/4885DPP9 1115/4885DPP7 768/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.