SCHEMBL27322136

SCHEMBL27322136

CCC(=O)c1ccc2c(c1)nc(NCCOCCOCCN)c1ccncc12

nearest known ligand 0.60

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 20/20 0.60
CSNK2A2 P19784 18/20 0.60
CSNK2B P67870 15/20 0.60
CSNK2A3 Q8NEV1 7/20 0.46
CLK2 P49760 1/20 0.46
HDAC1 Q13547 4/20 0.45
HDAC6 Q9UBN7 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27322142 0.90 CSNK2A1 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL30803613 0.90 CSNK2A1 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL27322160 0.89 CSNK2A2 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL30803645 0.89 CSNK2A2 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL25370461 0.83 CSNK2A1 (0.71) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL25370378 0.82 CSNK2A1 (0.62) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL29900390 0.82 CSNK2A2 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL25369036 0.82 CSNK2A2 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL30803369 0.81 CSNK2A1 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL26048826 0.81 CSNK2A2 (0.63) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed