SCHEMBL27322142

SCHEMBL27322142

COC(=O)c1ccc2c(c1)nc(NCCOCCOCCN)c1ccncc12

nearest known ligand 0.61

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CSNK2A1 P68400 19/20 0.61
CSNK2A2 P19784 16/20 0.61
CSNK2B P67870 13/20 0.61
CSNK2A3 Q8NEV1 6/20 0.50
CLK2 P49760 3/20 0.48
PARP1 P09874 1/20 0.47
HDAC1 Q13547 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803613 1.00 CSNK2A1 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL25370378 0.93 CSNK2A1 (0.62) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL30803369 0.92 CSNK2A1 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3HDAC1
SCHEMBL30803645 0.90 CSNK2A2 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL27322160 0.90 CSNK2A2 (0.61) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL27319864 0.90 CSNK2A1 (0.66) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL27322136 0.90 CSNK2A1 (0.60) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL27321691 0.90 CSNK2A1 (0.58) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL25287381 0.89 CSNK2A1 (0.66) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2
SCHEMBL25249993 0.88 CSNK2A1 (0.68) CSNK2A1CSNK2A2CSNK2BCSNK2A3CLK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024052692-A1 NOVEL COMPOUNDS AS CK2 INHIBITORS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-03-14 WO disclosed