SCHEMBL27324362

SCHEMBL27324362

N[C@@H](CS)C(=O)S(=O)(=O)O

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ PTGS1 P23219 2/20 0.50
▸ SLC7A11 Q9UPY5 1/20 0.50
▸ SLC22A6 Q4U2R8 1/20 0.36
▸ ENPEP Q07075 10/20 0.34
▸ ANPEP P15144 2/20 0.33
▸ PDE4A P27815 1/20 0.31
▸ PMP22 Q01453 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27324363 1.00 PTGS1 (0.50) PTGS1SLC7A11SLC22A6ENPEPANPEP
SCHEMBL7979726 0.80 PTGS1 (0.50) PTGS1SLC7A11SLC22A6ENPEPANPEP
Cysteine SCHEMBL431234 0.75 PTGS1 (0.80) PTGS1SLC7A11ENPEPANPEPPMP22
Cysteine SCHEMBL11127428 0.75 PTGS1 (0.80) PTGS1SLC7A11ENPEPANPEPPMP22
Cysteine SCHEMBL11127430 0.75 PTGS1 (0.80) PTGS1SLC7A11ENPEPANPEPPMP22
SCHEMBL2036153 0.75 SLC22A6 (0.36) SLC22A6PMP22
Cysteine SCHEMBL431233 0.75 PTGS1 (0.80) PTGS1SLC7A11ENPEPANPEPPMP22
Cysteine SCHEMBL7728523 0.73 PTGS1 (0.76) PTGS1SLC7A11ENPEPANPEPPMP22
Cysteine SCHEMBL9490762 0.73 PTGS1 (0.76) PTGS1SLC7A11ENPEPANPEPPMP22
Cysteine SCHEMBL8817362 0.73 PTGS1 (0.76) PTGS1SLC7A11ENPEPANPEPPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121577901-A Urine metabolism marker combination for distinguishing benign kidney diseases from kidney cancers and application thereof 哈尔滨脉图精准技术有限公司 2026-02-27 — — CN claimed
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (NO) 2026-04-30 — — US disclosed
EP-4732845-A2 SELECTIVE REDUCTION OF CYSTEINE RESIDUES IN IL-17 ANTIBODIES Novartis AG (CH) 2026-04-29 — — EP disclosed
CN-121577901-A Urine metabolism marker combination for distinguishing benign kidney diseases from kidney cancers and application thereof 哈尔滨脉图精准技术有限公司 2026-02-27 — — CN disclosed
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2026-01-20 — — US disclosed
WO-2025099157-A1 ABSOLUTE QUANTIFICATION OF ISOFORMS OF A PROTEIN OF INTEREST BY INTERNAL CALIBRATION BASED ON A TOP-DOWN LC-MS APPROACH Institut National de la Santé et de la Recherche Médicale (FR) 2025-05-15 — — WO disclosed
US-20250034241-A1 SELECTIVE REDUCTION OF CYSTEINE RESIDUES IN IL-17 ANTIBODIES NOVARTIS AG (CH) 2025-01-30 — — US disclosed
EP-4389143-A2 SELECTIVE REDUCTION OF CYSTEINE RESIDUES IN IL-17 ANTIBODIES Novartis AG (CH) 2024-06-26 — — EP disclosed
WO-2024088066-A1 SARCOPENIA DIAGNOSIS MARKER AND USE THEREOF 生物岛实验室 2024-05-02 — — WO disclosed
US-20220315650-A1 SELECTIVE REDUCTION OF CYSTEINE RESIDUES IN IL-17 ANTIBODIES NOVARTIS AG (CH) 2022-10-06 — — US disclosed
CN-108883345-B Method for protein purification UCB生物制药私人有限公司 2022-09-13 — — CN disclosed
US-20220249644-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens VESTLANDETS INNOVASJONSSELSKAP AS (VIS) (NO) 2022-08-11 — — US disclosed
US-11292833-B2 Selective reduction of cysteine residues in IL-17 antibodies NOVARTIS AG (CH) 2022-04-05 — — US disclosed
CN-1029976-C Process for reducing methionine sulfoxide residues LILLY CO ELI (US) 1995-10-11 — — CN disclosed
CN-1031538-A The method of reducing methionine sulfoxide residues LILLY CO ELI (US) 1989-03-08 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260115268-A1 Heat-Stable Enterotoxins Mutants as Antidiarrheal Vaccine Antigens SCN8A, SCN9A, VIP PTGS1 3465/4885SLC7A11 762/4885SLC22A6 780/4885
US-11292833-B2 Selective reduction of cysteine residues in IL-17 antibodies IL17A, IL23R, IL15RA PTGS1 1073/4885SLC7A11 588/4885SLC22A6 1412/4885
US-20250034241-A1 SELECTIVE REDUCTION OF CYSTEINE RESIDUES IN IL-17 ANTIBODIES IL17A, IL23R, IL15RA PTGS1 1073/4885SLC7A11 588/4885SLC22A6 1412/4885
US-20220315650-A1 SELECTIVE REDUCTION OF CYSTEINE RESIDUES IN IL-17 ANTIBODIES IL17A, IL23R, IL15RA PTGS1 1073/4885SLC7A11 588/4885SLC22A6 1412/4885
US-12527853-B2 Heat-stable enterotoxins mutants as antidiarrheal vaccine antigens VIP, MLEC, SEC16A PTGS1 4430/4885SLC7A11 601/4885SLC22A6 948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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