Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27323561 | 0.98 | ELANE (0.43) | ELANETTRDDX3XBAZ2BBAZ2A | |
| SCHEMBL9131035 | 0.87 | ELANE (0.44) | ELANETTRDDX3XGAATDP1 | |
| SCHEMBL5674095 | 0.83 | ELANE (0.47) | ELANEBAZ2BBAZ2AGAAKDM4E | |
| SCHEMBL7862817 | 0.82 | MPL (0.47) | ELANEBAZ2BBAZ2AGAATDP1 | |
| SCHEMBL9637470 | 0.80 | TTR (0.47) | TTRGAATDP1KDM4EALDH1A1 | |
| SCHEMBL7862807 | 0.80 | ELANE (0.47) | ELANEBAZ2BBAZ2AGAATDP1 | |
| SCHEMBL2761135 | 0.80 | ELANE (0.47) | ELANEBAZ2BBAZ2AGAATDP1 | |
| SCHEMBL8772779 | 0.80 | TTR (0.46) | TTRDDX3XGAATDP1KDM4E | |
| SCHEMBL29659353 | 0.77 | TDP1 (0.48) | TTRGAATDP1KDM4EALDH1A1 | |
| SCHEMBL153905 | 0.77 | TDP1 (0.48) | TTRGAATDP1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1028521-C | Therapeutic agents | BOOTS CO PLC (GB) | 1995-05-24 | — | — | CN | disclosed |
| CN-1072173-A | Therapeutical agent | BOOTS CO PLC (GB) | 1993-05-19 | — | — | CN | disclosed |